Description: Sisters focused on four very different sisters living in Winnetka, Illinois. Their recently deceased father, Thomas Reed, a doctor, had been absent and a workaholic, while their long-suffering mother, Beatrice, turned to alcoholism to cope with his neglect and affairs. Having always wanted sons, their father had called the girls by male versions of their full names: Alexandra was called Alex; Theodora, Teddy; Georgiana, Georgie; and Francesca, Frankie.